Wetenschap

Wetenschap staat centraal in alles bij Cerule.

Ze dagen de status quo uit en streven er voortdurend naar om baanbrekende gezondheids- en schoonheidsoplossingen te vinden en te ontwikkelen die positieve veranderingen teweegbrengen om u te helpen een langer, gezonder en gelukkiger leven te leiden. Met deze missie heeft Cerule al meer dan tien jaar een positieve impact op talloze levens wereldwijd.

Uitleg over Stamcel in het Nederlands

Klinich onderzoek (Engels)

Een samenvatting van eerder en huidig onderzoek dat relevant is voor onze huidige en toekomstige producten, vindt u hier.

(Momenteel alleen beschikbaar in het Engels)


NEW SCIENTIFIC STUDY: Introduction to Cerule’s unique, proprietary blend of Collagen and Cyactiv, CollagenActiv


Summary report on in vitro tests carried out on Aphanizomenon flos-aquae (AFA) samples for cosmetic use.
In vitro efficacy study evaluation of repairing effect of a Aphanizomenon flos-aquae (AFA) on cell culture.

Mobilization of human CD34+CD133+ and CD34+CD133 stem cells in vivo by consumption of an extract from Aphanizomenon flos-aquae—B related to modulation of CXCR4 expression by an L-selectin ligand. Cardiovascular Revascularization Medicine 8 (2007) 189–202


Kushak R, Drapeau C, Van Cott E (Winter HH 2000) Favorable effects of blue-green algae Aphanizomenon flos-aquae on rat plasma lipids. JANA vol. 2 (3): 59-65

Drapeau C, Aphanizomenon flos-aquae and the nervous system, attention deficit disorder, depression and mood elevation.


Hart A, Zaske L, Patterson K, Drapeau C, Jensen G (2007) Natural killer cell activation and modulation of chemokine receptor profile in vitro by an extract from the cyanophyta Aphanizomenon flos-aquae. Journal of Medicinal Food, 10(3): 435-441


Jensen G, Carter S, Redman K, Benson K, Ehmann A, Guthrie J, Turner J, Drapeau C (2009) Cognitive enhancement and immune modulating properties of an antioxidant-rich microalgae extract - AFAninPlus. SupplySide West 2009 Poster Session


Pugh N, Ross S, ElSohly H, ElSohly M, Pasco D (2001) Isolation of three high molecular weight polysaccharide preparations with potent immunostimulatory activity from Spirulina platensis, Aphanizomenon flos-aquae and Chlorella pyrenoidosa. Planta Medica Journal of Medicinal Plant and Natural Product Research, 67, 737 742


Schaeffer D, Krylove V (2000) Anti-HIV activity of extracts and compounds from algae and cyanobacteria. Ecotoxicology and Environmental Safety, 45, 208-227


Lahitova N, Doupovcova M, Zvonar J, Chandoga J, Hocman G (1994) Antimutagenic properties of fresh-water blue-green algae. Folia Microbiol, 39(4), 301-307


Romay C, Armesto J, Remirez D, Gonzalez R, Ledon N, Garcia I (1998) Antioxidant and Anti-inflammatory Properties of C-phycocyanin from Blue-green Algae. Inflammation Research, 47: 36-41


Gonzalez R, Rodriguez S, Romay C, Ancheta O, Gonzalez A, Armesto J, Remirez D, Merino N (1999) Anti-inflammatory activity of phycocyanin extract in acetic acid-induced colitis in rats. Pharmaccological Research, 39(1):55-9


Romay C, Ledon N, Gonzalez R (1998) Further studies on anti-inflammatory activity of phycocyanin in some animal models of inflammation. Inflammation Research, 47(8):334-8


Reddy C, Bhat VB Kiranmai G, Reddy M, Reddanna P, Madyastha K (2000) Inhibition of cyclooxygenase-2 by C-phycocyanin, a biliprotein from Spirulina platensis. Biochemical and Biophysical Research Communications, 277(3):599-603


Remirez D, Gonzáles A, Merino N, González R, Ancheta O, Romay C, Rodrigues S (1999) Effect of phycocyanin in zymosan-induced arthritis in mice-phycocyanin as an antiarthritic compound. Drug Development Research, 48:70-75


Rimbau V, Camins A, Romay C, Gonzáles R, Pallas M (1999) Protective effects of C-phycocyanin against kainic acid-induced neuronal damage in rat hippocampus. Neuroscience Letters, Dec 3: 276:75-78


Rimbau V, Camins A, Pubill D, Sureda F, Romay C, González R, Jimenéz A, Escubedo E, Camarasa J, Pallás M (2001) C-Phycocyanin protects cerebellar granule cells from low potassium/serum deprivation-induced apoptosis. Naunyn-Schmiedeberg’s Archives of Pharmacology, 364:96-104.


Romay C, Ledón N, González R (2000) Effects of phycocyanin extract on prostaglandin E2 levels in mouse ear inflammation test. Arzneimittel.-Forschung./Drug Research, 50(II), Nr12, 1106-1109


Bhat, V, Gaikwad N, Madyastha K (1998) Hepatoprotective effect of C-phycocyanin: protection for carbon tetrachloride and R-(+)-pulegone-mediated hepatotoxicty in rats. Biochemical and Biophysical Research Communications, 249(2):428-31


Bhat V, Madaystha K (2000) C-Phycocyanin: A potent peroxyl radical scavenger in vivo and in vitro. Biochemical and Biophysical Research Communications, 275, 20-25


Carter SG, Redman KA, Benson KF, Ehmann A, Guthrie J, Norris L, Turner J, Jensen, GS. Analegisic and anti-inflammatory properties of a novel phycocyanin-rich microalgae extract, CyaninPlusTM. SSW09 poster session.


Romay C, González R, Ledón N, Remirez D, and Rimbau V (2003) C-Phycocyanin: a biliprotein with antioxidant, anti-inflammatory and neuroprotective effects. Current Protein and Peptide Science, 4, 000-000 1


Khan M, Vradharaj S, Ganesan L, Shobha J, Naidu M, Parinadi N, Tridandapani S, Kutala V, Kuppusamy P (2006) C-phycocyanin protects against ischemia-reperfusion injury of heart through involvement of p38 MAPK and ERK signaling. American Journal of Physiology Heart and Circulatory Physiology, May 290 (5) H2136-45


Benedetti S, Benvenuti F, Pagliarani S, Francogli S, Scoglio S, Canestrari F (2004) Antioxidant properties of a novel phycocyanin extract from the blue-green alga Aphanizomenon flos-aquae. Life Sciences, Sep 24;75(19):2353-62


Hsiao G, Chou P, Shen M, Chou D, Lin C, Sheu J (2005) C-phycocyanin, a very potent and novel platelet aggression inhibitor from Spirulina platensis. Journal of Agricultural Food Chemicals, Oct 5;53 (20):7734-40


Jensen GS, Attridge VL, Carter SG, Guthrie J, Ehmann A, Benson, KF (2016) Consumption of an aqueous cyanophyta extract derived from Arthrospira platensis is associated with reduction of chronic pain: results from two human clinical pilot studies. Nutrition and Dietary Supplements 2016:8 65–70


Sabelli H, Fink P, Fawcett J, Tom C (1996) Sustained antidepressant effect of PEA replacement. Journal of Neuropsychiatry and Clinical Neurosciences, 8(2):168-71


Szavo A, Billett, E, Turner J (2001) Phenylethylamine, a possible link to the antidepressant effects of exercise? Journal of Sports Medicine, 35, 342-343